Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | (Depression) Mental health problems ever diagnosed by a professional__20544-both_sexes-11 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL34187, DESMOSOME, AND ICHTHYOSIS VULGARIS |
| Enrichment Score (ES) | 0.4916847 |
| Normalized Enrichment Score (NES) | 1.1831316 |
| Nominal p-value | 0.17234468 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.997 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | EVPL | 619 | 1.352 | 0.0960 | Yes |
| 2 | FLG | 787 | 1.255 | 0.2081 | Yes |
| 3 | PPL | 903 | 1.194 | 0.3172 | Yes |
| 4 | DSC3 | 2143 | 0.843 | 0.3289 | Yes |
| 5 | DSG1 | 2684 | 0.750 | 0.3710 | Yes |
| 6 | PKP2 | 3116 | 0.690 | 0.4135 | Yes |
| 7 | DSC1 | 3761 | 0.614 | 0.4366 | Yes |
| 8 | LORICRIN | 3826 | 0.607 | 0.4917 | Yes |
| 9 | PKP3 | 7257 | 0.359 | 0.3329 | No |
| 10 | DSG2 | 7473 | 0.348 | 0.3544 | No |
| 11 | DSP | 7480 | 0.348 | 0.3877 | No |
| 12 | KRT77 | 7870 | 0.329 | 0.3977 | No |
| 13 | DSG3 | 7998 | 0.323 | 0.4218 | No |
| 14 | CASP14 | 8223 | 0.313 | 0.4394 | No |
| 15 | KRT10 | 11513 | 0.197 | 0.2729 | No |
| 16 | KRT1 | 12732 | 0.160 | 0.2196 | No |
| 17 | TMEM43 | 13186 | 0.146 | 0.2082 | No |
| 18 | BLMH | 14378 | 0.110 | 0.1517 | No |
| 19 | PERP | 14699 | 0.102 | 0.1435 | No |
| 20 | FLG2 | 15764 | 0.071 | 0.0903 | No |
| 21 | PKP1 | 15968 | 0.065 | 0.0851 | No |
| 22 | CDSN | 16276 | 0.055 | 0.0731 | No |
| 23 | JUP | 16439 | 0.050 | 0.0688 | No |
| 24 | DSC2 | 16460 | 0.049 | 0.0724 | No |
| 25 | SERPINB12 | 17396 | -0.000 | 0.0196 | No |
| 26 | KRT2 | 17473 | -0.000 | 0.0153 | No |
